Research
Applied methods, not noise.
Our research efforts focus on applied methods that bridge cutting-edge bioinformatics and practical analytics for the organisations we serve. Every analysis is reproducible, interpretable, and decision-ready.
How we work.
Reproducible, interpretable, decision-ready — every analysis is built to be acted on.
Computational Biology
Algorithms for variant analysis, expression profiling, biomarker discovery, and patient stratification.
Data & ML Methods
Techniques for predictive modelling, risk scoring, and pattern detection in large-scale biomedical datasets.
Decision Support
Translating complex models into interfaces and workflows that support clinicians, scientists, and business teams.
Selected Publications
80+ papers in leading world journals.
Spanning oncology, neuroscience, cardiology, endocrinology, reproductive medicine, and more.
Molecular mechanisms underlying gliomas and glioblastoma pathogenesis revealed by bioinformatics analysis of microarray data.
DOI →02Archives of Gynaecology & ObstetricsIdentification of differentially expressed genes regulated by molecular signature in breast cancer-associated fibroblasts by bioinformatics analysis.
DOI →03Journal of Molecular NeuroscienceIdentification of Important Invasion-Related Genes in Non-functional Pituitary Adenomas.
DOI →04Pathology — Research & PracticeBioinformatics analysis of gene expression profiles to diagnose crucial and novel genes in glioblastoma multiforme.
DOI →05Gene ReportsInvestigation into the underlying molecular mechanisms of non-small cell lung cancer using bioinformatics analysis.
DOI →06DiagnosticsMining Featured Biomarkers Linked with Epithelial Ovarian Cancer Based on Bioinformatics.
DOI →07Reproductive Biology & EndocrinologyIdentification of key pathways and genes in polycystic ovary syndrome via integrated bioinformatics analysis and prediction of small therapeutic molecules.
DOI →08AIMS NeuroscienceIdentification of potential and novel target genes in pituitary prolactinoma by bioinformatics analysis.
DOI →09Frontiers in EndocrinologyIdentification of Key Pathways and Genes in Obesity Using Bioinformatics Analysis and Molecular Docking Studies.
DOI →10Bioinformatics & Biology InsightsPotential Molecular Mechanisms and Remdesivir Treatment for Acute Respiratory Syndrome Coronavirus 2 / COVID-19 Through RNA Sequencing and Bioinformatics Analysis.
DOI →11MedicinaBioinformatics and Next-Generation Data Analysis for Identification of Genes and Molecular Pathways in Subjects with Diabetes and Obesity.
DOI →12Therapeutic Advances in Cardiovascular DiseaseIdentification of biomarkers, pathways, and potential therapeutic targets for heart failure using next-generation sequencing data and bioinformatics analysis.
DOI →13Bioinformatics & Biology InsightsIdentification and Interaction Analysis of Molecular Markers in Pancreatic Ductal Adenocarcinoma by Bioinformatics and Next-Generation Sequencing Data Analysis.
DOI →14Middle East Fertility Society JournalThe identification of key genes and pathways in polycystic ovary syndrome by bioinformatics analysis of next-generation sequencing data.
DOI →15Italian Journal of MedicineScreening of the key genes and signalling pathways for schizophrenia using bioinformatics and next-generation sequencing data analysis.
DOI →16Genome Instability & DiseaseBioinformatics and next-generation sequencing data analysis to identify key genes and pathways influencing Parkinson's disease.
DOI →From disease to gene in one glance.
Hover or focus a disease to reveal the target gene identified by NESMATRIX research. Each filled cell is a known target; recurring genes flag across diseases.
Alzheimer's Disease →
| Disease | Target gene(s) |
|---|---|
| Alzheimer's Disease | HSP90AA1, ESR with FN3 |
| Bipolar Disorder | UBB, CNBD2, UBE2D1, CAV1 |
| Coronary Artery Disease | EGR1, SIRT1 |
| Chronic Obstructive Pulmonary Disorder | LMNA, MYC, PHGDH, SHMT2 |
| Hypertrophic Cardiomyopathy | LGALS3, ESR1 |
| Heart Failure | AXL Kinase |
| Inflammatory Bowel Disease | ERBB2, HNF4A |
| Major Depressive Disorder | ONECUT1, YWHAG, CDK2, VCAM1 |
| Multiple Sclerosis | LCK, CFTR |
| Ovarian Cancer | HSPB3, GNA01, FOXA2 |
| Recurrent Implantation Failure | APP, HSP90AA1 |
| Schizophrenia | NEDD4, MYC |
| Sepsis | SOCS1 |
| Type 2 Diabetes Mellitus | KEAP1, INSIG2 |
| Type 1 Diabetes Mellitus | FN1 |
| Obesity & Cardiometabolic Disorders | ER1, C3AR1 |
| Rheumatoid Arthritis | MYC, SQSTM1 |
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